In this paper， the effects of aronia melanocarpa polyphenols （AMP） from aronia melanocarpa fructus on blood pressure regulation and intestinal flora in rats with hypertension induced by high-salt and high-sugar diet were investigated. After Waster rats were fed with 20% fructose water and 5% NaCl for 21 days， their feces were collected for intestinal flora richness analysis， flora analysis， Heatmap analysis and comparative analysis of the COG database. The results showed that AMP had a positive effect on hypertension， and the antihypertensive effect of polyphenols does not simply increase with the increase of concentration. And medium dose AMP （The concentration is 1.4 mg/kg， and the daily intragastric dose is 7.5 mL/kg） had the best antihypertensive effect， the antihypertensive effect reached 11.6%. In addition， AMP can not only regulate the intestinal microenvironment， but also improve the intestinal function of hypertension rats， which is beneficial to improve the therapeutic effect of hypertension diseases. Compared with conventional antihypertensive drugs， AMP had less effect on intestinal flora， and the richness of some beneficial bacteria was increased， such as Lactobacillaceae increased by 59.2% respectively compared with the normal group. Therefore， this study provides theoretical basis for the use of AMP as functional factors in the regulation of hypertension and the preparation of relevant functional foods