In this paper， the preparation technology of celery fiber hollow capsule was studied with Chinese Pharmacopoeia as index， and the effects of various factors on the properties of celery fiber hollow capsule were analyzed. The results of single factor showed that the sol temperature， sol time， drying temperature and water loss rate had significant effects on the Pharmacopoeia index of the capsule. Through RSM design， the optimized preparation parameters of celery fiber plant hollow capsules were obtained as follows： the sol temperature was 74 ℃， the sol time was 32 min， the drying temperature was 36 ℃， and the water loss rate was 85%. The preparation of celery fiber plant hollow capsules met the requirements of Chinese Pharmacopoeia. Verification of experimental results table it is clear that the relative error between the experimental results and the theoretical prediction is less than 5%. This study provides a theoretical basis for the preparation of a new type of plant hollow capsules.