Disadvantages such as poor stability and compatibility， limit the health efficacy exertion and application of tea polyphenols. In this paper， casein （CS） was modified by multipolar pH transformation combined with ultrasonic simultaneous thermal induction to improve its stability of encapsulate and transport EGCG. The EGCG ternary nanoparticle emulsion was established by vortex incubation to establish a self-assembly model， and high-load EGCG nanoparticles were obtained. The encapsulation rate of the target product reached 90%-95%， and the loading rates were all higher than 305 μg/mg， which achieved a significant increase in the loading of EGCG（P<0.05）. In this study， the emulsion and storage stability of EGCG nanoparticles were enhanced while ensuring higher loading and encapsulation rates. Compared with the blank group， the thermodynamic stability and release properties in vitro of nano-encapsulated EGCG improved significantly， which was conducive to promoting the high-value utilization of EGCG and the expansion and extension of application fields.