文章摘要
GA-zein-cur核壳结构分散体系的构建及工艺条件优化
GA-zein-cur core-shell structure dispersionsystem construction and technological condition optimization
投稿时间:2016-07-31  修订日期:2016-07-31
DOI:
中文关键词: 水溶性,姜黄色素,zein,反溶剂,操作条件
英文关键词: water-solubility, curcumin, zein, anti-solvent, operating  conditions
基金项目:浙江省食品科学与工程重中之重一级学科
作者单位E-mail
王美 浙江工商大学食品与生物工程学院 1745034101@qq.com 
傅玉颖 浙江工商大学食品与生物工程学院 webfu@126.com 
倪俊杰 浙江工商大学食品与生物工程学院  
李可馨 浙江工商大学食品与生物工程学院  
沈亚丽 浙江工商大学食品与生物工程学院  
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中文摘要:
      采用反溶剂法制备GA-zein-cur分散体系,探讨不同的操作条件(反溶剂加入方式和速度、搅拌速度、溶剂类型以及浓度、溶剂和反溶剂的体积比)对GA-zein-cur分散体系形成的影响。研究结果表明:在1000rpm条件下采用正加入法快速加入反溶剂,以80%乙醇-水溶液作为溶剂,溶剂和反溶剂体积比为1:2.5时制得的GA-zein-cur分散体系粒径较小,粒度分布较窄,同时姜黄色素的包埋率也有大幅度的提高,随着溶剂-反溶剂体积比的减小,制备的分散体系的平均粒径和PDI值均变小,从而制得的分散体系更均一,稳定,透明。
英文摘要:
      GA-zein-cur dispersion system was prepared by anti-solvent precipitation.The effects of key parameters of the process (the adding method of anti-solvent, the mixing speed, the type and concentration of solvent, the volume ratio of solvent and anti-solvent,) on the size and size distribution of the nanoparticles was studied. The results showed that with the anti-solvent quickly added to the solvent in 1000 rpm, the GA-zein-cur nanoparticles were more stable. To prepare the GA-zein-cur nanoparticles with 80%(v/v) ethanol-in-water mixtures as solvent, 1:2.5(v/v) ratios of solvent: anti-solvent were used. With the decrease of the solvent-anti solvent volume ratio,the average partical size and PDI values are smaller of the disperse system.Under these conditions, the GA-zein-cur dispersion system can be prepared with better uniformity, stability and transparency.
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