L-α-Glycerylphosphorylcholine (L-α-GPC) is a choline phospholipid derivative naturally present in the human body， which is easily absorbed and utilized by the body. It has been allowed to be used in food in China， the United States， Japan and other countries and regions. Studies have shown that L-α-GPC can improve cognitive function， regulate emotional state， and improve physical performance. To provide science-based guidance for both academia and industry， the relevant experts in food science， clinical medicine， sports medicine and nutrition were organized by Chinese Institute of Food Science and Technology to form this consensus after systematic literature review and seminars， which may foster the evidence-based understanding of L-α-GPC and to promote its application in food industry in China.