To compare the differences in the characteristic composition of milk from Guanzhong dairies goat raised under different husbandry practices， we conducted an analysis of oligosaccharide composition， epidermal growth factor (EGF) content， and lipid profile in two groups of goat milk collected from individual households and breeding farms. High-performance liquid chromatography (HPLC) and mass spectrometry (MS) were employed for the qualitative and quantitative analysis of oligosaccharides and lipids in the goat milk， while the enzyme-linked immunosorbent assay (ELISA) was utilized for the quantitative determination of EGF content. The results indicated that the variety of oligosaccharides and their content， as well as the EGF content， were higher in the milk from the breeding farm group compared to the individual household group. Specifically， the content of 3'-sialyllactose sodium salt (3'-SL) and EGF in the milk from the breeding farm group was (15.46 ± 3.56) mg/L and (67.87 ± 11.11) ng/mL， respectively， which was significantly higher than that in the milk from the individual household group， which was(9.88 ± 0.48) mg/L and(51.56 ± 3.95) ng/mL(P<0.01). Lipidomic analysis revealed that the levels of lysophosphatidylethanolamine (LPE)， phosphatidylethanolamine (PE)， and phosphatidylglycerol (PG) in the milk from the breeding farm group were significantly higher than those in the milk from the individual household group (P<0.05)， while the content of triglycerides (TG) was significantly lower (P<0.001). The milk from the breeding farm group showed significantly higher levels of 3'-SL， EGF， and certain lipids compared to the milk from the individual household group.