乳酸菌粘附肠道上皮细胞的研究进展
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“十三五”国家重点研发计划项目(2017YFD0400303)


The Research Progress on the Adherence of Lactic Acid Bacteria to Intestinal Epithelial Cells
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    摘要:

    近些年来,乳酸菌因对人体健康功能的促进作用而成为研究热点。目前普遍将乳酸菌的粘附能力作为评价乳酸菌益生性的首要指标。乳酸菌对肠道上皮细胞或细胞外基质组分的粘附会引起机体产生有益的生物学效应。本文从乳酸菌的黏附素和宿主受体的相互作用阐述乳酸菌的粘附机制以及影响其粘附能力的内、外因。归纳目前国内外有关评价乳酸菌粘附特性的方法,以期为乳酸菌粘附特性的研究和应用奠定理论基础。

    Abstract:

    In recent years, lactic acid bacteria has become a research hotspot for its promotion of human health function. At present, the adhesive ability of lactic acid bacteria is widely used as the primary indicator to evaluate the probiotic nature of lactic acid bacteria. The adhesion ability of lactic acid bacteria to intestinal epithelial cells or extracellular matrix components can cause beneficial biological effects in the body. The adhesion mechanism of lactic acid bacteria is preliminarily elucidated from the interaction between the adhesin of lactic acid bacteria and host receptor. At the same time, the external and internal factors affecting the adhesion capacity of lactic acid bacteria are also reviewed. And the progress of the research methods for evaluating the adhesion characteristics of lactic acid bacteria at home and abroad is summarized in order to lay a theoretical foundation for the research and application of the adhesive characteristics of lactic acid bacteria.

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占萌;李春;李慧臻;李娜;焦文姝;王成风;霍贵成;李柏良.乳酸菌粘附肠道上皮细胞的研究进展[J].中国食品学报,2020,20(11):341-350

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  • 在线发布日期: 2020-12-04
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