Cultured meat is meat products that are directly cultured from animal cells in vitro. It has many advantages such as low energy consumption, low greenhouse gas emissions and low land utilization rate. Cultured meat is considered as one of the feasible alternatives to the traditional meat production technology in the future, with high potential commercial value. However, as a new type of food, it is difficult to supervise food safety according to the existing food safety assessment system. At present, countries are still trying to establish a food safety supervision system for cultured meat products. By 2022, Singapore and the United States have given the green light to cultured meat products. The cultured chicken nuggets produced by Eat Just have been successfully marketed in Singapore and Upside successfully passed the pre-market consultation regulated by U.S. Food And Drug Administration"s (FDA). The food safety risk assessment system for cultured meat products formulated by the two countries have important reference and research value for the relevant regulatory authorities in other countries and regions, as well as practitioners in the cell culture meat industry. In order to promote the construction of safety assessment system of cultured meat products in China and the development of cultured meat industry, this review summarized and analyzed the exploration of food safety assessment of cultured meat in Singapore, the United States, the European Union and China. In addition, some suggestions on the construction of cultured meat regulatory system in China are put forward.