Cancer is a important question of human health because of its disease rate and fatality rate. Bioactive peptides with the advantages of biological compatibility， targeting property， no immunogenicity， and low toxicity has become the latest must-haves in the prevention and treatment of cancer drugs， and has become the focus of researcher. In this paper， the antitumor activity of bioactive peptides， mechanism were analysed and reviewed， so as to help the researcher to provide ideas and guidance of the development of anticancer bioactive peptide.