This study investigated the selenium content of marketed millet in 10 regions of China. It was found that selenium content of millet is very different， and the selenium content is generally not high. In addition， this article also reviewed selenium-enriched techniques of millet， selenium speciation and metabolism in grains； elucidates associated health disorders or risks due to the consumption of Se-deficient or Se-rich foods. Finally， we prospected the research and development of the seleniferous product of grains.