An analytical method for biogenic amines commonly（cadaverine， histamine， tyramine， tryptamine， pyridoxamine hydrochloride， spermine， spermidine， putrescine and 2-phenylethylamine） in Baijiu and Chinese rice wine by pre-column derivatization-HPLC was developed. The biogenic amines in Baijiu and Chinese rice wine were derived with dansyl chloride， separated by the C18 chromatographic column（250 mm×4.6 mm， 5 μm）. The mixture of acetonitrile and water （0.01 mmol/L ammonium acetate， 0.1% formic acid） were served as the mobile phase at a flow rate of 0.8 mL/min and the ultraviolet （UV） detection wavelength was 254 nm. The results showed that in the concentration range of 0.5-50 mg/L， each of the 9 biogenic amine presented good linear correlation （R2 > 0.998）. After the addition of a mixed standard solution of biogenic amines to Chinese yellow wine， the recovery rates were 83.30%-114.7%， with relative standard deviations （RSDs） below 4.56%， and the limit of detection for each component was 0.07-0.22 mg/L. Hence， the pre-column derivatization-HPLC method in this experiment could be used to separate and detect the biogenic amines in Baijiu and Chinese rice wine accurately.