Objective： The effects of rice paste and biscuit rich in Chinese medicine homologous food extract （rice paste rich in Poria cocos-yam extract， and biscuit rich in Hericium erinaceus extract） on ethanol-induced gastric mucosal injury in rats was investigated in this study. Methods： Acute gastric mucosal injury model was established by orally administering absolute ethanol to rats. Rats were randomly divided into normal group， model group， positive group， three Poria cocos-yam extract treatment groups （low， medium， high dose）， three rice paste treatment groups （low， medium， high dose）， three Hericium erinaceus extract treatment groups （low， medium， high dose）， and three biscuit treatment groups （low， medium， high dose）. On this basis， the effects of four test substances on ethanol-induced gastric mucosal injury in rats were further explored （observation of rat growth and gastric mucosal injury）. Results： Compared with the normal group， the model group showed obvious bleeding bands， a large number of bleeding locations， gastric mucosal glandular structure disorder， epithelial cell shedding and severe congestion， and significantly increased gastric mucosal injury index. Compared with the model group， the gastric bleeding bands and bleeding locations of rats in each dose group of the four kinds of treatment were significantly reduced. In addition， the gastric mucosal damage for rats was also significantly reduced. Conclusion： The four kinds of treatment have better preventive effects on ethanol-induced acute gastric mucosal injury in rats. Meanwhile， the effect of Poria cocos-yam extract and the rice paste in each dose was better than Hericium erinaceus extract and the biscuit. The results in this study can provide data support for the development of health products for improving gastrointestinal function.