Probiotics can improve functional dyspepsia （FD）， but probiotics are strain-specific， and the role of probiotics and their mechanism by which probiotics improve FD symptoms are not well studied. In this study， the effect of Lactobacillus paracasei LC-37 Lactobacillus beverage on improving functional dyspepsia and regulating intestinal flora was studied. Methods： a total of 30 subjects with functional dyspepsia were recruited for a 21-day clinical trial， including a 7-day emptying period， a 14-day ingesting period. During the ingesting period， subjects will drink 200 g LC-37 Lactobacillus beverage（the total number of viable Lactobacillus paracasei LC-37 is 5×108 CFU/g， 100 g/bottle） per day. On the 7-day emptying period and the 28-day ingesting period， fecal samples were collected， and clinical symptom scores were evaluated by doctor. Intestinal flora of fecal samples was analyzed by 16S rDNA high-throughput sequencing. Results： there were 29 effective subjects. After ingesting the LC-37 Lactobacillus beverage for 14 days， the clinical symptoms in FD population was significantly improved （P<0.05）， and the composition of the intestinal flora was changed， the abundance of beneficial Bifidobacterium， Prevotella_9 and Alistipes genus increased， and Lactobacillus increased significantly， and the abundance of harmful Dorea genus decreased. Conclusion： ingesting LC-37 fermented milk for 14 days， functional dyspepsia could be improved significantly， and intestinal flora was regulated.