To investigate the differences in physicochemical properties and solubilization efficiencies of octenyl succinic anhydride esterified starches (OSAS) with different linear/branched chain ratios， the corresponding OSAS were prepared using corn starches with different linear/branched chain ratios as raw material and octenyl succinic anhydride (OSA) as an esterification agent， and their degrees of substitution (DS) of OSA， physicochemical properties and solubilizing effects on hesperetin were determined. The results showed that after OSA esterification， the starch with high amylose content had a high DS value. The higher the amylopectin content in OSAS， the greater its swelling capacity and the higher its transparency， while the higher the amylose content in OSAS， the easier it was to sediment. The esterification of starch by OSA mainly occurred on the surface of starch granules. OSAS with high amylose content had a significant solubilizing effect on hesperetin， with its solubility increased by 5.4 folds. Conclusion: OSAS with different linear/branched chain ratios showed significant differences in physicochemical properties， and these differences were attributed to the content ratio of amylose to amylopectin. The higher amylose content in OSAS， the more obvious its solubilization efficiency to hesperetin.