The imbalance between energy intake and energy consumption leads to the increase of adipose tissue and the disorder of lipid metabolism， which leads to obesity， diabetes， cardiovascular disease and other metabolic diseases. Resveratrol (RSV) is a natural astragalus polyphenols compound， which can effectively improve obesity and other metabolic diseases by regulating lipid synthesis and oxidative decomposition， adipokine secretion， adipose tissue heat production and inhibiting inflammation. At present， the regulation of lipid metabolism by RSV has attracted extensive attention and made great progress. Therefore， this paper reviews the recent studies on the regulation of lipid metabolism by RSV， in order to provide more theoretical basis for the application of RSV in improving metabolic diseases.