Endocrine disruptors (EDCs) in food are important risk factors for food safety. In particular， with the continuous development of the food packaging market， the migration of EDCs such as plasticizers or surfactants in food contact materials (FCMs) into food add the range of foodborne EDCs. Clarifying the toxic effects of foodborne EDCs is important for protecting food safety. In this paper， we systematically compiled and analyzed the current status of research on the toxic effects of foodborne EDCs from four aspects， including epidemiology， model organisms， alternative toxicology and computational toxicology， combined with metabolomics， transcriptomics and molecular biology. The application status， advantages， disadvantages and interconnections of different toxic effect evaluation techniques were discussed. Prospects for the application of different evaluation methods and techniques were proposed. The aim of this paper is to provide valuable information for the study of the toxic effects of foodborne EDCs.