The natural antibacterial substance of bacteriocin produced by lactic acid bacteria is an ideal substitute for chemical preservatives and antibiotics. Cell communication triggers various life activities via signal transmission. In this paper， the cell communication mechanism for producing bacteriocin was described from the aspects including the sources of different inducing signals， the induction mechanism of different signals， the mechanism of bacteriocin synthesis， the multi-cell communication in co-cultivation， and the signal network of quorum sensing (QS) in complex environment. And the research progress on the cell communication mechanism of LAB was systemically introduced. These will provide important reference for promoting the research and application of LAB bacteriocins.