Breast milk research， which is the focus of maternal and infant health research， is the golden key to unlocking the mysteries of early life nutrition. The purpose of this paper is to focus on the research trends of breast milk science and infant formula manufacturing technology， and to clarify the innovative direction of maternal and infant nutrition research in China. Based on the analysis of literature and industrial research， top six research topics was illustrated， including nutritional needs of early life， depth exploration of milk composition， effects assessment of breast milk， innovative manufacturing of functional raw materials， testing technology and evaluation methods of raw materials， efficient retention of active ingredient， covering the maternal and child nutrition scientific research， functional material research and infant formula manufacturing technology， thus providing important reference for scientific research of breast milk and development of infant formula industrial.