Objective:The anti-obesity effect of Pu-erh tea and its ingredients has long been known， but few studies on this effect among different Pu-erh tea has been taken into account. In this experiment， two kinds of Pu-erh tea with obvious differences， namely RAPT (Pu-erh raw tea) and RIPT (Pu-erh ripe tea)， were used to prepare tea soup to feed C57BL6/J mice on a HFD (high-fat diet) to observe the differences in the intervention effects. The results shown that RAPT and RIPT not only had anti-obesity effects in terms of blood fat indicators， organ tissue changes， and intestinal flora， but also have significant differences in the intervention effects shown. RAPT can reduce blood TC and TG levels after 2 weeks of feeding， while Pu-erh ripe tea does not have this effect until 8 weeks； RAPT could reduce the level of LDL-C in the blood while RIPT could increase HDL- C. In liver lipid metabolism， both RAPT and RIPT could remarkably reduce the formation of fat droplets in the liver. After 8 weeks of feeding， RAPT significantly increased the abundance of Akkermansia， norank_f__Muribaculaceae， and Bacteroides in the intestinal flora and decreased the abundance of Romboutsia. RIPT could increase the abundance of Lactobacillus， norank_f__Muribaculaceae， and Bacteroides in the intestinal flora， and down-regulate the abundance of Romboutsia and Erysipelatoclostridium.