The purpose of this study was to evaluate the immunomodulatory properties of chicken soup， chicken meat and their complexes. Gushi chicken(two year) was used as raw material to prepare chicken soup powder and chicken meat powder， respectively， and their amino acid compositions were determined. Chicken soup， chicken meat and their complexes were given to immunosuppressive mice induced by intraperitoneal injection of cyclophosphamide. The body weight， immune organ index， cytokines， immunoglobulins， spleen immunohistochemical analysis and histopathology of the mice were measured. The effects of immune chicken meat and their complexes on the above indicators were analyzed from the aspects of cellular immunity and humoral immunity. The results showed that chicken soup， chicken meat and their complexes improved the immune capacity of immunosuppressed mice. Chicken soup significantly increased the blood hemoglobin content [(133.33±4.07) g/L]， serum IgA content [(341.99±17.89) pg/mL] and serum IgG content [(1 988.75±96.56) pg/mL] of immunosuppressed mice. Compared with chicken soup， the expression of CD4+ on spleen cell surface was significantly increased. Their complex could increase thymus index [(1.62±0.47) mg/g]， improve spleen and ileum tissue injury， stimulate interferon-γ secretion [(1 355.83±71.73) pg/mL]， and restore Th1/Th2 balance. Conclusion: This study showed that chicken soup， chicken meat and their complexes had an improvement on the immune regulation function of immunosuppressed mice， and the comprehensive effect of chicken soup was better than that of chicken.