负载白藜芦醇的大麦醇溶蛋白/海藻酸丙二醇酯复合纳米颗粒的制备及表征
作者:
作者单位:

(1.中国农业大学食品科学与营养工程学院 北京 100083;2.农业农村部农业转基因生物安全评价(食用)重点实验室 北京 100083)

作者简介:

通讯作者:

中图分类号:

基金项目:

2018年国家科技重大专项RNA干扰新型转基因产品食用安全评价关键技术与评价指南研究(2018ZX0801102B-002)


Fabrication and Characterization of Resveratrol Loaded with Hordein / Propylene Glycol Alginate Composite Nanoparticles
Author:
Affiliation:

(1.College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083;2.Key Laboratory of Safety Assessment of Genetically Modified Organism (Food Safety),Ministry of Agriculture and Rural Affairs, Beijing 100083)

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    以大麦醇溶蛋白(hordein)、海藻酸丙二醇酯(PGA)为原料,通过溶剂蒸发法制备大麦醇溶蛋白-海藻酸丙二醇酯复合纳米颗粒(Hordein/PGA),并对白藜芦醇进行包封。结果表明,随海藻酸丙二醇酯添加量的增加,Hordein/PGA的粒径由1 654.9 nm逐渐下降至475.9 nm。同时Hordein/PGA的电位均为负值,并随海藻酸丙二醇酯添加量的增大由-3.62 mV下降至-8.04 mV。红外光谱结果显示:大麦醇溶蛋白与海藻酸丙二醇酯主要通过氢键、静电吸引及疏水相互作用结合。以Hordein/PGA1∶1对白藜芦醇进行包封,构建三元复合纳米颗粒(Hordein/PGA/Res),白藜芦醇的包封率可达87%。红外光谱和X射线衍射分析表明白藜芦醇与大麦醇溶蛋白、海藻酸丙二醇酯有效结合。Hordein/PGA/Res经85 ℃处理30 min后白藜芦醇保留率为88%,显著高于游离白藜芦醇保留率(73%);经6 h紫外光辐射处理后白藜芦醇保留率可提高约16%。

    Abstract:

    In this study, Hordein/PGA composite nanoparticles were fabricated by solvent evaporation using hordein and PGA as materials, and resveratrol was encapsulated. The results indicated that the particle size of Hordein/PGA decreased from 1 654.9 nm to 475.9 nm with the increase of PGA content. The potentials of Hordein/PGA were negative, and the value decreased from -3.62 mV to -8.04 mV with the increase of PGA content. Fluorescence spectra showed that hydrogen bonds, hydrophobic effects and electrostatic interactions contributed to the formation of Hordein/PGA composite nanoparticles. Resveratrol was encapsulated by Hordein/PGA1:1 to construct ternary composite nanoparticles (Hordein/PGA/Res), and the encapsulation rate of resveratrol reached 87%. Fourier transform infrared and X-ray diffraction demonstrated that resveratrol was effectively combined with hordein and PGA. The retention rate of resveratrol in Hordein/PGA/Res after heat treatment at 85 ℃ for 30 min was 88%, which remarkably higher than the free resveratrol (73%). And the retention rate of resveratrol increased by about 16% after 6 h ultraviolet light treatment.

    参考文献
    相似文献
    引证文献
引用本文

赵天瑜,唐荣,金雨楠,梅晓宏.负载白藜芦醇的大麦醇溶蛋白/海藻酸丙二醇酯复合纳米颗粒的制备及表征[J].中国食品学报,2023,23(9):89-98

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2022-09-30
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2023-11-22
  • 出版日期:
文章二维码
版权所有 :《中国食品学报》杂志社     京ICP备09084417号-4
地址 :北京市海淀区阜成路北三街8号9层      邮政编码 :100048
电话 :010-65223596 65265375      电子邮箱 :chinaspxb@vip.163.com
技术支持:北京勤云科技发展有限公司

漂浮通知


×
《中国食品学报》杂志社招聘编辑