膳食中双酚类化合物的污染水平和风险评估
作者:
作者单位:

(1.广元市疾病预防控制中心 四川广元 628000;2.杭州市疾病预防控制中心 杭州 310006)

作者简介:

通讯作者:

中图分类号:

基金项目:

广元市科技计划项目(19ZDYF0016)


Bisphenols in Diets: Contaminated Levels and Risk Assessment
Author:
Affiliation:

(1.Guangyuan Center for Disease Prevention and Control, Guangyuan 628000, Sichuan;2.Hangzhou Center for Disease Control and Prevention, Hangzhou 310006)

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    采用超高效液相色谱-串联质谱(UPLC-MS/MS)对278份广元市售食品中8种双酚类化合物(BPs)进行分析,并估算不同年龄和不同性别组人群的BPs每日膳食摄入量,评估居民通过膳食摄入BPs的情况和健康风险。结果表明:大部分(76.3%)市售食品含有BPs,含量在检出限(LOD)~59.08 μg/kg之间,平均3.12 μg/kg,其中罐头食品、谷类、水产类以及蔬菜中ΣBPs含量较高。BPA和BPS是主要的污染物,分别占总BPs的77.9%%和14.4%。不同年龄和不同性别组人群BPs每日膳食暴露水平在42.59~96.54 ng/kg bw/d之间,BPA对膳食暴露的贡献率最高,其次是BPS。BPs总暴露量随着年龄的增长呈下降趋势。2~19岁(发育关键期)人群的ΣBPs每日膳食摄入量(87.96 ng/kg bw/d)明显高于19岁以上人群的成人组(48.05 ng/kg bw/d)。各组人群由饮食接触引起的BPs健康风险较低,其从膳食接触到的BPs均低于欧洲食品安全局暂定的BPA日允许摄入量(t-TDI,4 μg/kg bw/d)。因BPA类似物的生产和应用在全球范围呈上升趋势,故其引起的健康风险应持续被关注。

    Abstract:

    Bisphenols(BPs) are suspected posing potential endocrine disrupting properties. Occurrence of BPs has been reported in environmental matrices. BPs might migrate into foodstuffs through food packaging materials or contaminated water and soil. Information on the occurrence of bisphenols, other than BPA, in foodstuffs, however, is scarce. Dietary exposure is of paramount importance way for human health. In this study, eight BPs, including BPA, BPS, BPP, BPB, BPAP, BPAF, BPF and BPZ, were analyzed in market foodstuffs (N = 278) collected from Guangyuan, Sichuan, China, using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) foodstuffs were divided into ten categories of beverages, dairy products, eggs, cquatic foods, cereals, meats, fruits, vegetables, canned food and packaged drinking water. Bisphenols were found in the majority (76.3%) of the food samples, and the total concentrations of bisphenols (ΣBPs: sum of eight bisphenols) were in the range of below the limit of detection (LOD) to 59.08 μg/kg, with an overall mean value of 3.12 μg/kg. The higher overall mean concentration of ΣBPs was found in canned food, cereals, cquatic foods and vegetables. The predominant bisphenol analogues found in foodstuffs were BPA and BPS, which accounted for 77.9% and 14.4% of the total BPs concentrations, respectively. On the basis of measured concentrations and daily ingestion rates of foods, the daily dietary intakes of bisphenols (calculated from the mean concentration) were estimated to rang from 42.59 ng/kg bw/d to 96.54 ng/kg bw/d for different age and gender groups. BPA contributed to the majority of the total intakes of the BPs, followed by BPs. The daily dietary intakes of BPs showed a decrease with the growth of the age. It should be noted that dietary intakes of people aged 2-19 year old (critical time of development, 87.96 ng/kg bw/d) were obviously higher than that of aged above 19(48.05 ng/kg bw/d). Based on the t-TDI set by EFSA (4 μg/kg bw/d for BPA), the BPs through dietary intake pose low risks on the general population even summarization exposure levels of different BPs. However, the production and application of BPA analogues are increasing worldwide, and the health risks caused by BPA analogues should be continuously concerned.

    参考文献
    相似文献
    引证文献
引用本文

佐鹏,谭学蓉,刘少颖,杨容,李波,穆芳,石卜芳.膳食中双酚类化合物的污染水平和风险评估[J].中国食品学报,2023,23(12):219-228

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2022-12-29
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2024-01-23
  • 出版日期:
文章二维码
版权所有 :《中国食品学报》杂志社     京ICP备09084417号-4
地址 :北京市海淀区阜成路北三街8号9层      邮政编码 :100048
电话 :010-65223596 65265375      电子邮箱 :chinaspxb@vip.163.com
技术支持:北京勤云科技发展有限公司

漂浮通知


×
《中国食品学报》杂志社招聘编辑