Objective: Lycium barbarum， Hippophae rhamnoides L. and calcium fruit are unique food and medicine food in the north of China， in order to develop the nutrients of three kinds of fruits at a deep level， calcium fruit pulp (purity 100%)， sea buckthorn pulp (purity 100%)， wolfberry pulp (purity 100%) three kinds of raw materials in accordance with the volume ratio of 2∶1.5∶1 mixing and blending to make a sweet and sour calcium fruit composite fruit syrup， to explore its functional composition and weight loss. Methods: Inductively coupled plasma mass spectrometry (ICP-MS) was used to determine the trace elements of the composite fruit pulp， high-phase liquid chromatography (HPLC) was used to determine the vitamins and carotenoids， and liquid chromatography-mass spectrometry (LC-MS) was used to determine the polyphenolic compounds and organic acid compounds. An obese mouse model was established to investigate the weight loss effect of the composite fruit pulp on obese mice. The results showed that the composite fruit pulp was rich in a variety of functional components， including (73.671±4.918) μg/L of calcium， (503.333±2.054) ng/mg of vitamin B2， and (8.345±0.091) μg/mL of rutin. Compared with the model group， the dose group showed a significant decrease in the body mass of the mice and a significant decrease in the triglyceride content after the intervention of the composite fruit pulp. content was significantly reduced (P＜0.05). Conclusion: Compound fruit pulp has a significant improvement effect on obese mice， and this study provides data support for the nutritional and health care effects of calcium fruit compound fruit pulp， and provides a new nutritional intervention method for obesity prevention.