人体肠道菌群主要特征的专家共识
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(中国食品科学技术学会益生菌分会 北京 100048)

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Scientists Consensus on Human Gut Microbiota
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(Probiotics Society of the Chinese Institute of Food Science and Technology, Beijing 100048)

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    摘要:

    从19世纪科学家开始探索肠道菌群与人体健康的关系,到近年来提出“肠-脑轴”“肠-X轴”等新的概念,肠道菌群对人体健康的影响早已成为不争的事实。然而,由于人体肠道菌群的组成具有地域和个体差异性,且易受到外在因素(如膳食、药物、运动等)和内在因素(种族、年龄和血型等)的影响,因此,目前国内外对“人体健康肠道菌群”尚无明确的定义。研究表明,健康人体肠道存在的基石物种对肠道菌群的物种多样性和功能多样性具有较大的贡献,而肠道菌群的失调则会引发一系列健康问题,可通过改善膳食营养结构、生活方式,补充益生菌、益生元等调节肠道菌群。本文依据国内外科学文献,在研究与分析影响肠道菌群主要因素的基础上,凝练出人体肠道菌群的主要特征并形成共识,旨在为深入研究“健康肠道菌群”及相关技术开发与行业发展提供参考。

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    Since scientists began to explore the relationship between gut microbiota and human health in the 19th century, and with the introduction of new concepts such as the ‘gut-brain axis’ and ‘gut-X axis’ in recent years, the impact of gut microbiota on human health has been an undisputed fact. However, the composition of human gut microbiota is subject to geographic and individual variability, making it susceptible to the influence of extrinsic factors (such as diet, medications, and exercise) and intrinsic factors (such as race, age, and blood type). Therefore, there is no universally accepted definition of ‘healthy human gut microbiota’ both domestically and internationally. Studies have shown that cornerstone species in the healthy human gut play a significant role in the species diversity and functional diversity of gut microbiota, while the imbalance in gut microbiota will cause a series of health problems, which can be regulated by improving the dietary nutritional structure, lifestyle, and supplementing probiotics and prebiotics. Based on scientific literature both domestically and internationally, and through research and analysis of the main factors affecting the gut microbiota, this paper summarizes the main characteristics of the human gut microbiota and establishes a consensus, aiming to provide a reference for the further exploration of ‘healthy gut microbiota’ and the development of related technologies and industries.

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中国食品科学技术.人体肠道菌群主要特征的专家共识[J].中国食品学报,2024,24(7):460-470

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  • 收稿日期:2024-05-10
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  • 在线发布日期: 2024-08-22
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