脂肪酸摄入形式对肠屏障的影响及食用油摄入模式探讨
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(1.江南大学食品学院 江苏无锡 214122;2.食品科学与资源挖掘全国重点实验室 江苏无锡 214122)

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国家自然科学基金青年科学基金项目(32201936);江苏省自然科学基金青年科学基金项目(BK 20221076)


Influence of Fatty Acid Intake Forms on Intestinal Barrier and Exploration of Edible Oil Intake Patterns
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(1.School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu;2.State Key Laboratory of Food Science and Resources, Wuxi 214122, Jiangsu)

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    摘要:

    不同食用油脂脂肪酸组成不同,其营养特性存在差异,长期不平衡膳食油脂或脂肪酸摄入,已被证实与慢性代谢类疾病发生风险具有相关性,而肠道组织屏障在此过程中发挥着重要作用。本文介绍肠屏障和食用油脂摄入对肠屏障功能的影响,综述食用油摄入水平和脂肪酸摄入类型[饱和脂肪酸(SFA)、单不饱和脂肪酸(MUFA)和多不饱和脂肪酸(PUFA)]对肠屏障影响的研究进展。鉴于脂肪酸的摄入比例对于维持机体代谢平衡的重要性,重点探讨ω6/ω3型PUFA摄入比例对肠屏障功能的影响。针对当前我国居民食用油摄入形式和脂肪酸平衡摄入的研究现状,提出基于优化脂肪酸摄入比例,调整食用油摄入模式的若干意见,旨在为改善肠道屏障功能,降低社会慢性代谢疾病风险提供参考。本文对于了解不同脂肪酸的营养特性,并从改善肠屏障功能的角度,提升食用油加工与营养品质,优化摄入模式,助力实现“健康中国”战略目标具有一定的意义。

    Abstract:

    The diversities of the fatty acid compositions contribute to the differences of the nutritional characteristics of the different edible oils. Long term unbalanced dietary edible oil or fatty acid consumption have been evidenced to be correlated with an increased risk of developing chronic metabolic diseases, and the gut mucosal barrier displayed prominent influences during this process. Therefore, in the present review paper, the types of the gut mucosal barrier, as well as the influences of the dietary oils intake on the gut barrier functions were introduced. Moreover, the research progress about the influences of dietary oil intake and the fatty acid species (i.e. saturated fatty acids, SFA; monounsaturated fatty acids, MUFA; polyunsaturated fatty acids, PUFA) on the intestinal barrier had been summarized. Considering the importance of the fatty acid intake ratio for maintaining the metabolic balance of the humans, the effects of ω6/ω3 PUFA intake ratio on gut barrier functions also had been elucidated. Finally, based on the forms of edible oil consumption by the Chinese residents and the current research status about the concepts of balanced fatty acids intake, several considerations were proposed for adjusting the edible oil intake mode based on optimizing the fatty acid intake ratio. All of the aims were to provide references for improving gut barrier functions and reducing the risks of chronic metabolic diseases. The present work could be of some significance for understanding the nutritional characteristics of different fatty acids, improving the processing and nutritional quality of the edible oils, optimizing fatty acid intake patterns, and assisting in achieving the strategic targets of 'Healthy China' from the perspective of improving intestinal barrier functions.

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叶展,刘元法.脂肪酸摄入形式对肠屏障的影响及食用油摄入模式探讨[J].中国食品学报,2025,25(2):451-462

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  • 收稿日期:2024-02-21
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  • 在线发布日期: 2025-03-24
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