In order to improve the comprehensive utilization value of soybean dregs and reduce resource waste， soybean dregs were used as raw materials， mixed evenly with Rice noodles， corn starch and monofatty acid glyceride， and then the soybean dregs recombined rice was prepared by twin-screw extruder. The soybean residue reconstituted rice is extruded to convert some insoluble dietary fiber into soluble dietary fiber， and the dietary fiber content is significantly higher than that of ordinary rice. The water solubility index， water absorption index， water holding index， oil absorption index， and swelling index of soybean residue reconstituted rice are (469.25±1.77) g/g， (5.42±0.05)%， (7.77±0.03) g/g， (3.68±0.11) g/g， and (8.58±0.11) mL/g， respectively， which are significantly higher than those of ordinary rice (P<0.05). The soybean residue recombinant rice reduced the increase in body weight of mice and increased their glucose tolerance. The area under the blood glucose curve of mice in the soybean residue recombinant rice group was (1 313.83±45.17) mmol· h/L， significantly lower than that of the blank group. Through 16s rDNA genomic analysis， it was found that the number of species(4 625.04)， Chao1 index(5 124.28) and Shannon index(8.71) of intestinal flora in the soybean recombination rice group were higher than those in the blank group. The recombination rice from soybean recombination increased the richness and diversity of intestinal flora， increased the abundance of Bacteroidetes at the phyla level， and decreased the abundance of Lactobacillaceae at the taxonomic level.