In order to prepare the blood lipid interfering compound apple juice， 10 kinds of polyphenols and basic physicochemical indexes of 20 apple samples were analyzed and evaluated by principal component analysis（PCA） and cluster analysis（CA）. Then， based on the polyphenolic monomer with hypolipidemic effect， two kinds of apple varieties with high blood-fat reducing efficacy and high fruit juice quality were selected. The results showed that the contents of polyphenolic monomers in 20 apple varieties were quite different. The contents of chlorogenic acid of Aksu and Qinguanwas were the top two， and the contents of catechin， epicatechin， and phlorizinwere also among the top. Additionally， 10 polyphenolic monomers were analyzed by principal component and cluster analysis with chlorogenic acid， epicatechin， catechins and chloroalin as the main component of polyphenol monomers with the effect of blood lipid intervention. Combined with fruit juice quality evaluation， Akesu and Qinguan were identified as 2 apple varieties with high blood lipid intervention and good juice quality.