The objective of this study is to investigate the effect of active modified atmospheres （Active MAP） on the inhibition of mold. In this study， Cladosporium link was used as test material， and the initial gas proportion of O2/CO2 including 60%O2+40%CO2， 70%O2+30%CO2， 80%O2+20%CO2， 90%O2+10%CO2， and natural air （ck） were employed. During storage at （28±0.5） ℃， the colony diameter， spore amount， cell membrane permeability， release of cellular contents， and subsequent effects of growth curve， polygalacturonase （PG）， polymethylgalacturonases （PMG）， superoxide dismutase （SOD）， and catalase （CAT） were periodically measured. The results showed that O2/CO2 active MAP significantly inhibited the colony expansion rate and sporulation rate of Cladosporium link， reduced the activity of SOD， CAT， PG， and PMG， destroyed the cell membrane integrity， increased the cell membrane permeability and release of cellular contents. Furthermore， the antibacterial effect was significantly enhanced along with the increase of CO2 ratio. This study provides a theoretical basis for mold control during fruits and vegetables storage.