In this study， tape 2 diabetic mellitus(T2DM) were given high fat diet with 10% highland barley and 5%， 10%， 20% germinated highland barley respectively to study the activities of highland barley and germinal highland barley in lowering blood glucose and blood lipid. The results showed that 5%， 10% and 20% germinated highland barley can reduce the fasting plasma glucose， insulin level and insulin sensitive index， serum total cholesterol and low density lipoprotein levels and the content of apolipoprotein B， improve the content of apolipoprotein A and the activity of lecithin cholesterol acyltransferase， to alleviate the glucose and lipid metabolism disorder in T2DM.