Abstract:Functional dyspepsia(FD) is a functional gastrointestinal disease, but its etiology and pathogenesis have not been fully elucidated. Studies have shown that there is a correlation between the composition of intestinal flora and FD, and the disturbance of gastrointestinal flora may be one of the main mechanisms of FD. At present, the treatment of functional dyspepsia is limited, and there are safety problems. A class of active bacteria known as probiotics can control the body's gastrointestinal homeostasis, nutritional digestion and absorption, and energy balance when taken in certain dosages. Therefore, it has potential advantages to alleviate FD by regulating intestinal flora by probiotics, targeting intestinal microorganisms. This paper summarized the research progress of probiotics in improving functional dyspepsia by regulating intestinal flora, so as to provide reference basis for probiotics to improve FD.