Fabrication and Characterization of Resveratrol Loaded with Hordein / Propylene Glycol Alginate Composite Nanoparticles
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(1.College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083;2.Key Laboratory of Safety Assessment of Genetically Modified Organism (Food Safety),Ministry of Agriculture and Rural Affairs, Beijing 100083)

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    Abstract:

    In this study, Hordein/PGA composite nanoparticles were fabricated by solvent evaporation using hordein and PGA as materials, and resveratrol was encapsulated. The results indicated that the particle size of Hordein/PGA decreased from 1 654.9 nm to 475.9 nm with the increase of PGA content. The potentials of Hordein/PGA were negative, and the value decreased from -3.62 mV to -8.04 mV with the increase of PGA content. Fluorescence spectra showed that hydrogen bonds, hydrophobic effects and electrostatic interactions contributed to the formation of Hordein/PGA composite nanoparticles. Resveratrol was encapsulated by Hordein/PGA1:1 to construct ternary composite nanoparticles (Hordein/PGA/Res), and the encapsulation rate of resveratrol reached 87%. Fourier transform infrared and X-ray diffraction demonstrated that resveratrol was effectively combined with hordein and PGA. The retention rate of resveratrol in Hordein/PGA/Res after heat treatment at 85 ℃ for 30 min was 88%, which remarkably higher than the free resveratrol (73%). And the retention rate of resveratrol increased by about 16% after 6 h ultraviolet light treatment.

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  • Received:September 30,2022
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  • Online: November 22,2023
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