People's health has become an important factor restricting Chinese social development. It has become an international consensus to promote health through precise nutritional intervention. However， nutrition and health personnel are scarce in China. Based on analysis of the knowledge system of nutrition and health industry， comparison of the development track of the domestic and international related discipline of nutrition and health， this study clarified the academic and theoretical basis of the inter-discipline Nutrition and Health Science. Meanwhile， the connotation and extension of the inter-discipline Nutrition and Health Science were also clarified. This study provides theoretical guarantee for the construction of the inter-discipline Nutrition and Health Science， so as to provide a cradle for the cultivation of innovative nutrition and health talents in China， assist the development of health industry， and realize the great vision of healthy China.