Ponkan peel is rich in glycoside flavones and polymethoxylated flavones. To utilize adequately the two flavone， the synchronized extraction from ponkan peel was carried out， whose technology was optimized by single factor and orthogonal test， based on the the extraction rate of main flavonoid monomer of ponkan peel. The obtained crude extract was purified by the macroporous resin column chromatography. The results showed that the optimized extracting technology was a concentration of 60% ethanol， solid-liquid ratio (g/mL) of 1∶40， extracting temperature of 75 ℃ and extracting time of 110 min， by which the total extracting ratio of seven flavones was (72.63±1.53) mg/g. Through the single factor experiment， the better purified conditions by the macroporous resin column chromatography were a loading sample volumn of 170 mL， loading sample mass concentration of 2.5 g/L in 30% ethanol solution， flow rate of 1 mL/min and elution concentration of 80% ethanol， under which the contents of hesperiding， nobiletin and tangeretin in purified extract were 4.6， 2.3， 1.45 folds of those of crude extract. Conclusion: The glycoside flavones and polymethoxylated flavones in ponkan peel were extracted synchronously at a higher extracting ratio， whose contents were enhanced further by the following purification by the macroporous resin column chromatography. The research results can provide the evidence and reference for the extraction of multiple flavones and comprehensive utilization of ponkan peel.