As a natural bioactive substance， mulberry anthocyanins are rich in polyphenolic components， predominantly cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside， which exhibit multiple physiological activities including potent antioxidant effects， suppression of inflammatory responses， inhibition of cancer cell proliferation， and improvement of glucose-lipid metabolism disorders， demonstrating diverse health-promoting effects. Currently， it has been widely applied in fields such as the food industry， pharmaceuticals， cosmetics， and animal husbandry， serving as natural colorants， functional additives， anti-aging ingredients， and other applications. This paper systematically reviewed the chemical properties， absorption-metabolism pathways， biological functions， and cross-industrial application advances of mulberry anthocyanins， providing a theoretical basis for their further development and value-added utilization.